Étude randomisée à l’aveugle pour comparer l’efficacité et la tolérance d’un laser YAG 1064 nm de 650 microsecondes à un laser excimer 308 nm pour le traitement du psoriasis vulgaire léger à modéré.

Mark S. Nestor MD PhD,a,b Daniel Fischer DO MS,a David Arnold DOa

Les options actuelles pour le traitement du psoriasis comprennent des modalités systémiques et topiques. Les thérapies systémiques comprennent des inhibiteurs immunitaires, des modulateurs immunitaires et, pour les maladies modérées à graves, des agents biologiques.1 Principalement, pour le psoriasis léger à modéré, les traitements topiques comprennent des pommades, des bains médicamenteux contenant de la diastase ou des extraits de plantes, et la photothérapie. La photothérapie est sécuritaire, efficace et n’entraîne pas les effets secondaires des médicaments systémiques.2 Le laser excimer 308 nm est considéré comme une photothérapie de première intention pour le psoriasis en plaques topique.2 L’efficacité et la sécurité de ce laser ont été largement évaluées pour le traitement du psoriasis.3-9 L’avantage du laser excimer est sa capacité à traiter les lésions psoriasiques avec de fortes doses de rayonnement monochromatique tout en épargnant la peau non affectée.2 Trois protocoles ont été développés pour optimiser le traitement : la dose minimale d’érythème, l’induration et la dose minimale de cloques.7Un nouveau laser Nd:YAG 1064 nm de 650 microsecondes a été introduit en 2009 par Khatri et ses collègues qui ont utilisé le laser pour éliminer les poils indésirables. 10 Depuis, d’autres chercheurs11, 12 ont utilisé le laser 650 microsecondes pour traiter la peau de couleur, l’onychomycose,13 les télangiectasies faciales14 et l’acné. 15 L’avantage du laser 650 microsecondes est que le traitement ne nécessite ni refroidissement ni anesthésie, car la durée de l’impulsion est inférieure ou égale au temps de relaxation thermique de la cible thérapeutique. Cette caractéristique minimise les cicatrices, les changements pigmentaires, les dommages thermiques aux tissus environnants et l’inconfort pendant ou après le traitement.15 Le laser 650 microsecondes a reçu l’approbation de la FDA pour le traitement du psoriasis. L’objectif principal de cette étude était de comparer la capacité du laser YAG pulsé de 650 microsecondes et 1064 nm (LightPod Neon®, Aerolase Corp, Tarrytown, NY) pour éliminer les plaques psoriasiques avec celle du laser excimer 308 nm (XTRAC Velocity 400®, PhotoMedex, Inc., Montgomeryville, PA). Les plaques étaient situées sur les membres des sujets atteints de psoriasis vulgaire léger à modéré.

Table of Contents

Hyperpigmentation

Photos Courtesy of Cheryl Burgess, MD.

Photos Courtesy of Jennifer Parker-Porter, MD.

Learn more about treating hyperpigmentation today.

Vascular Lesions

Photos Courtesy of Dr. Guilia Kasimova.

Photos Courtesy of Michael Gold, MD.

Learn more about treating vascular lesions today.

Rosacea / Redness

Photos Courtesy of Yelena Kipervas, DO.

Photos Courtesy of Dr. Nabil Fakih.

Learn more about treating rosacea and redness today.

Hair Removal

Photos Courtesy of Dr. Andrew Nnadi.

Photos Courtesy of Steik Spa.

Learn more about treating hair removal today.

PFB

Photos Courtesy of Dr. Michelle Henry.

Photos Courtesy of Wendy Roberts, MD.

Learn more about treating PFB today.

Scars

Photos Courtesy of Dr. William Watfa.

Photos Courtesy of Bradley Bloom, MD.

Learn more about treating scars today.

Autoimmune Disorders

Photos Courtesy of Dr. Passeron.

Photos Courtesy of Dr. Sakhiya.

Learn more about treating autoimmune disorders today.

Skin Rejuvenation

Photos Courtesy of Catie Cutler, LE.

Photos Courtesy of Chesahna Kindred, MD.

Learn more about skin rejuvenation today.

Acne

Photos Courtesy of Michael Gold, MD.

Photos Courtesy of Michael Gold, MD.

Learn more about treating acne today.

Staff Accountant / Junior Accountant

Aerolase Corporation, a leading aesthetic laser innovator, seeks a Staff Accountant / Junior Accountant. Having made the Inc. 5000 list as one of the world’s fastest growing private companies as well as annual best-in-class product awards, Aerolase has transformed the market with products that provide uniquely tolerable treatments to the patients and exceptionally high ROI for the practitioners. The company offers competitive and an exciting high-growth company culture.

Staff Accountant / Junior Accountant

• Provide support to the Controller and the management team
• Maintain day-to-day financial accounting functions, including A/P, A/R, expense tracking
• Support the month-end close process, ensuring accurate and timely monthly, quarterly, and year-end financial statements.
• Uploading annual budget and tracking actual to budget variances
• Use of financial reporting software
• Support external auditors and other required outside reporting requirements
• Participation in quarterly inventory reconciliations
• Assist team with projects such as policy creation, system implementation, client support etc.

• Some experience with and strong understanding of the monthly close process and technical accounting
• Detailed oriented, with ability to see the big picture
• Self-starter who can work independently and employ time management skills to meet deadlines.
• Knowledge of MS Excel (V-lookup, formulas, pivot tables).
• Strong interpersonal and communication skills
• Sound judgment and problem-solving skills

• Bachelor’s or master’s degree in Accounting a MUST, good understanding of GAAP
• 1-3 years’ experience in an accounting function (including internship)
• General Ledger/Operational Accounting experience
• Knowledge of Quickbooks or other reporting software a plus (more the better)
• Industry experience a plus

Senior Accountant

Aerolase Corporation, a leading aesthetic laser innovator, seeks a Senior Accountant. Having made the Inc. 5000 list as one of the world’s fastest growing private companies as well as annual best-in-class product awards, Aerolase has transformed the market with products that provide uniquely tolerable treatments to the patients and exceptionally high ROI for the practitioners. The company offers competitive and an exciting high-growth company culture.

Senior Accountant:

• Provide support to the Controller and the management team
• Own day-to-day financial accounting functions, including A/P, A/R, expense tracking
• Assist in establishing and maintaining policies & procedures in accordance with GAAP and Aerolase policy
• Key contributor to the month-end close process, ensuring accurate and timely monthly, quarterly, and year-end financial statements.
• Assist in the preparation of management reports – (cash management, various projections, month end reporting package)
• Involvement with the annual budget process
• Use of financial reporting software
• Support external auditors and other required outside reporting requirements
• Prepare and submit payroll
• Participation in quarterly inventory reconciliation to the perpetual
• Ad hoc projects

• Strong knowledge of the monthly close process and technical accounting

• Detailed oriented, with ability to see the big picture

• Experience in continuous improvement and accounting best practices

• Self-starter who can work independently and employ time management skills to meet deadlines.

• System savvy – ability to learn new financial software

• Intermediate knowledge of MS Excel (V-lookup, formulas, pivot tables).

• Global consolidations experience a plus

• Strong interpersonal and communication skills

• Sound judgment and problem-solving skills

• Bachelor’s or master’s degree in Accounting a MUST, good understanding of GAAP

• 3+ years’ experience working as a staff/senior accountant

• General Ledger/Operational Accounting experience a must

• Extensive knowledge of Quickbooks and other reporting software

• Prior involvement with system implementation

• Prior public accounting experience (any size firm) a plus

• Industry experience a plus

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