Estudio aleatorio, con enmascaramiento, para comparar la eficacia y tolerancia de un láser YAG de 650 microsegundos de 1064 nm con un láser excimer de 308 nm para el tratamiento de psoriasis vulgar de leve a moderada

Mark S. Nestor MD PhD,a,b Daniel Fischer DO MS,a David Arnold DOa

Las opciones actuales para el tratamiento de la psoriasis incluyen modalidades sistémicas y tópicas. Las terapias sistémicas incluyen inhibidores inmunológicos, moduladores inmunológicos y, para enfermedades de moderadas a severas, agentes biológicos.1 Principalmente, para la psoriasis leve a moderada, los tratamientos tópicos comprenden ungüentos, baños medicinales con diastasa o extractos de hierbas y fototerapia. La fototerapia es segura, eficaz y no provoca los efectos secundarios de los medicamentos sistémicos.2 El láser excimer de 308 nm se considera fototerapia de primera línea para la psoriasis tópica de placas.2 La eficacia y seguridad de este láser se ha evaluado ampliamente para el tratamiento de la psoriasis.3-9 La ventaja del láser excimer es su capacidad para tratar lesiones psoriásicas con altas dosis de radiación monocromática sin afectar la piel no afectada.2 Se han desarrollado tres protocolos para optimizar el tratamiento: la dosis mínima de eritema, la induración y la dosis mínima de ampollas. Un nuevo láser Nd: YAG de 650 microsegundos de 1064 nm fue introducido en 2009 por Khatri y sus colegas, quienes lo utilizaron para eliminar el vello no deseado.10 Desde entonces, otros investigadores11, 12 han utilizado el láser de 650 microsegundos para tratar la piel de color, onicomicosis,13 telangiectasias faciales,14 y acné.15 La ventaja del láser de 650 microsegundos es que el tratamiento no requiere enfriamiento ni anestesia porque la duración del pulso es más corta o igual que el tiempo de relajación térmica de la diana terapéutica. Esta característica minimiza las cicatrices, los cambios pigmentarios, el daño térmico a los tejidos circundantes y las molestias durante o después del tratamiento.15 El láser de 650 microsegundos ha recibido la aprobación de la FDA para el tratamiento de la psoriasis. El objetivo principal de este estudio fue comparar la capacidad del láser YAG pulsado de 650 microsegundos de 1064 nm (LightPod Neo®, Aerolase Corp., Tarrytown, NY) para eliminar las placas psoriásicas con el láser excimer de 308 nm (XTRAC Velocity 400®, PhotoMedex, Inc., Montgomeryville, PA). Se localizaron placas en las extremidades de sujetos con psoriasis vulgar de leve a moderada.

Table of Contents

Hyperpigmentation

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Photos Courtesy of Jennifer Parker-Porter, MD.

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Vascular Lesions

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Rosacea / Redness

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Hair Removal

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PFB

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Scars

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Autoimmune Disorders

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Skin Rejuvenation

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Acne

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Photos Courtesy of Michael Gold, MD.

Learn more about treating acne today.

Staff Accountant / Junior Accountant

Aerolase Corporation, a leading aesthetic laser innovator, seeks a Staff Accountant / Junior Accountant. Having made the Inc. 5000 list as one of the world’s fastest growing private companies as well as annual best-in-class product awards, Aerolase has transformed the market with products that provide uniquely tolerable treatments to the patients and exceptionally high ROI for the practitioners. The company offers competitive and an exciting high-growth company culture.

Staff Accountant / Junior Accountant

• Provide support to the Controller and the management team
• Maintain day-to-day financial accounting functions, including A/P, A/R, expense tracking
• Support the month-end close process, ensuring accurate and timely monthly, quarterly, and year-end financial statements.
• Uploading annual budget and tracking actual to budget variances
• Use of financial reporting software
• Support external auditors and other required outside reporting requirements
• Participation in quarterly inventory reconciliations
• Assist team with projects such as policy creation, system implementation, client support etc.

• Some experience with and strong understanding of the monthly close process and technical accounting
• Detailed oriented, with ability to see the big picture
• Self-starter who can work independently and employ time management skills to meet deadlines.
• Knowledge of MS Excel (V-lookup, formulas, pivot tables).
• Strong interpersonal and communication skills
• Sound judgment and problem-solving skills

• Bachelor’s or master’s degree in Accounting a MUST, good understanding of GAAP
• 1-3 years’ experience in an accounting function (including internship)
• General Ledger/Operational Accounting experience
• Knowledge of Quickbooks or other reporting software a plus (more the better)
• Industry experience a plus

Senior Accountant

Aerolase Corporation, a leading aesthetic laser innovator, seeks a Senior Accountant. Having made the Inc. 5000 list as one of the world’s fastest growing private companies as well as annual best-in-class product awards, Aerolase has transformed the market with products that provide uniquely tolerable treatments to the patients and exceptionally high ROI for the practitioners. The company offers competitive and an exciting high-growth company culture.

Senior Accountant:

• Provide support to the Controller and the management team
• Own day-to-day financial accounting functions, including A/P, A/R, expense tracking
• Assist in establishing and maintaining policies & procedures in accordance with GAAP and Aerolase policy
• Key contributor to the month-end close process, ensuring accurate and timely monthly, quarterly, and year-end financial statements.
• Assist in the preparation of management reports – (cash management, various projections, month end reporting package)
• Involvement with the annual budget process
• Use of financial reporting software
• Support external auditors and other required outside reporting requirements
• Prepare and submit payroll
• Participation in quarterly inventory reconciliation to the perpetual
• Ad hoc projects

• Strong knowledge of the monthly close process and technical accounting

• Detailed oriented, with ability to see the big picture

• Experience in continuous improvement and accounting best practices

• Self-starter who can work independently and employ time management skills to meet deadlines.

• System savvy – ability to learn new financial software

• Intermediate knowledge of MS Excel (V-lookup, formulas, pivot tables).

• Global consolidations experience a plus

• Strong interpersonal and communication skills

• Sound judgment and problem-solving skills

• Bachelor’s or master’s degree in Accounting a MUST, good understanding of GAAP

• 3+ years’ experience working as a staff/senior accountant

• General Ledger/Operational Accounting experience a must

• Extensive knowledge of Quickbooks and other reporting software

• Prior involvement with system implementation

• Prior public accounting experience (any size firm) a plus

• Industry experience a plus

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