Randomized, Investigator-Blinded Study to Compare the Efficacy and Tolerance of a 650-microsecond, 1064-nm YAG Laser to a 308-nm Excimer Laser for the Treatment of Mild to Moderate Psoriasis Vulgaris (Randomisierte, Prüfarzt-verblindete Studie zum Vergleich der Wirksamkeit und Verträglichkeit eines Nd:YAG-Lasers mit einer Pulsdauer von 650 μs und einer Wellenlänge von 1064 nm im Vergleich zu einem 308-nm-Excimer-Laser zur Behandlung von leichter bis mittelschwerer Psoriasis vulgaris)

Mark S. Nestor MD PhD,a,b Daniel Fischer DO MS,a David Arnold DOa

Aktuelle Optionen für die Behandlung von Psoriasis umfassen systemische und topische Modalitäten. Systemische Therapien umfassen Immuninhibitoren, Immunmodulatoren und bei mittelschweren bis schweren Erkrankungen biologische Wirkstoffe.1 Topische Behandlungen umfassen in erster Linie bei leichter bis mittelschwerer Psoriasis Salben, medizinische Bäder mit Diastase oder Kräuterextrakten und Phototherapie. Die Phototherapie ist sicher, wirksam und verursacht nicht die für systemische Medikamente üblichen Nebenwirkungen.2 Der 308-nm-Excimer-Laser gilt als First-Line-Phototherapie bei topischer Plaque-Psoriasis.2 Die Wirksamkeit und Sicherheit dieses Lasers wurde zur Behandlung von Psoriasis ausführlich untersucht.3–9 Der Vorteil des Excimer-Lasers ist seine Fähigkeit, psoriatische Läsionen mit hohen Dosen monochromatischer Strahlung zu behandeln und gleichzeitig die nicht betroffene Haut zu schonen.2 Zur Optimierung der Behandlung wurden drei Protokolle entwickelt: die minimale Erythemdosis, die Induration und die minimale Blasenbildungsdosis.7 Im Jahr 2009 wurde von Khatri und Kollegen ein neuartiger Nd: YAG-Laser mit einer Pulsdauer von 650 μs und einer Wellenlänge von 1064 nm zur Entfernung unerwünschter Haare eingeführt.10 Seitdem haben andere Wissenschaftler11, 12 den 650-μs-Laser verwendet, um dunkle Haut, Onychomykose,13 Teleangiektasien im Gesicht14 und Akne zu behandeln.15 Der Vorteil des 650-μs-Lasers besteht darin, dass die Behandlung keine Kühlung oder Anästhesie erfordert, da die Pulsdauer kürzer oder gleich der thermischen Relaxationszeit des therapeutischen Ziels ist. Diese Funktion minimiert Narbenbildung, Pigmentveränderungen, thermische Schäden des umliegenden Gewebes und Beschwerden während oder nach der Behandlung.15 Der 650-μs-Laser hat die FDA-Zulassung für die Behandlung von Psoriasis erhalten. Das Hauptziel dieser Studie war es, die Fähigkeit des Nd:YAG-Lasers mit einer Pulsdauer von 650 μs und einer Wellenlänge von 1064 nm (LightPod Neo®, Aerolase Corp., Tarrytown, NY), Psoriasis-Plaques zu entfernen, mit der des 308-nm-Excimer-Lasers (XTRAC Velocity 400®, PhotoMedex, Inc., Montgomeryville, PA) zu vergleichen. An den Gliedmaßen von Personen mit leichter bis mittelschwerer Psoriasis vulgaris befanden sich Plaques.

Table of Contents

Hyperpigmentation

Photos Courtesy of Cheryl Burgess, MD.

Photos Courtesy of Jennifer Parker-Porter, MD.

Learn more about treating hyperpigmentation today.

Vascular Lesions

Photos Courtesy of Dr. Guilia Kasimova.

Photos Courtesy of Michael Gold, MD.

Learn more about treating vascular lesions today.

Rosacea / Redness

Photos Courtesy of Yelena Kipervas, DO.

Photos Courtesy of Dr. Nabil Fakih.

Learn more about treating rosacea and redness today.

Hair Removal

Photos Courtesy of Dr. Andrew Nnadi.

Photos Courtesy of Steik Spa.

Learn more about treating hair removal today.

PFB

Photos Courtesy of Dr. Michelle Henry.

Photos Courtesy of Wendy Roberts, MD.

Learn more about treating PFB today.

Scars

Photos Courtesy of Dr. William Watfa.

Photos Courtesy of Bradley Bloom, MD.

Learn more about treating scars today.

Autoimmune Disorders

Photos Courtesy of Dr. Passeron.

Photos Courtesy of Dr. Sakhiya.

Learn more about treating autoimmune disorders today.

Skin Rejuvenation

Photos Courtesy of Catie Cutler, LE.

Photos Courtesy of Chesahna Kindred, MD.

Learn more about skin rejuvenation today.

Acne

Photos Courtesy of Michael Gold, MD.

Photos Courtesy of Michael Gold, MD.

Learn more about treating acne today.

Staff Accountant / Junior Accountant

Aerolase Corporation, a leading aesthetic laser innovator, seeks a Staff Accountant / Junior Accountant. Having made the Inc. 5000 list as one of the world’s fastest growing private companies as well as annual best-in-class product awards, Aerolase has transformed the market with products that provide uniquely tolerable treatments to the patients and exceptionally high ROI for the practitioners. The company offers competitive and an exciting high-growth company culture.

Staff Accountant / Junior Accountant

• Provide support to the Controller and the management team
• Maintain day-to-day financial accounting functions, including A/P, A/R, expense tracking
• Support the month-end close process, ensuring accurate and timely monthly, quarterly, and year-end financial statements.
• Uploading annual budget and tracking actual to budget variances
• Use of financial reporting software
• Support external auditors and other required outside reporting requirements
• Participation in quarterly inventory reconciliations
• Assist team with projects such as policy creation, system implementation, client support etc.

• Some experience with and strong understanding of the monthly close process and technical accounting
• Detailed oriented, with ability to see the big picture
• Self-starter who can work independently and employ time management skills to meet deadlines.
• Knowledge of MS Excel (V-lookup, formulas, pivot tables).
• Strong interpersonal and communication skills
• Sound judgment and problem-solving skills

• Bachelor’s or master’s degree in Accounting a MUST, good understanding of GAAP
• 1-3 years’ experience in an accounting function (including internship)
• General Ledger/Operational Accounting experience
• Knowledge of Quickbooks or other reporting software a plus (more the better)
• Industry experience a plus

Senior Accountant

Aerolase Corporation, a leading aesthetic laser innovator, seeks a Senior Accountant. Having made the Inc. 5000 list as one of the world’s fastest growing private companies as well as annual best-in-class product awards, Aerolase has transformed the market with products that provide uniquely tolerable treatments to the patients and exceptionally high ROI for the practitioners. The company offers competitive and an exciting high-growth company culture.

Senior Accountant:

• Provide support to the Controller and the management team
• Own day-to-day financial accounting functions, including A/P, A/R, expense tracking
• Assist in establishing and maintaining policies & procedures in accordance with GAAP and Aerolase policy
• Key contributor to the month-end close process, ensuring accurate and timely monthly, quarterly, and year-end financial statements.
• Assist in the preparation of management reports – (cash management, various projections, month end reporting package)
• Involvement with the annual budget process
• Use of financial reporting software
• Support external auditors and other required outside reporting requirements
• Prepare and submit payroll
• Participation in quarterly inventory reconciliation to the perpetual
• Ad hoc projects

• Strong knowledge of the monthly close process and technical accounting

• Detailed oriented, with ability to see the big picture

• Experience in continuous improvement and accounting best practices

• Self-starter who can work independently and employ time management skills to meet deadlines.

• System savvy – ability to learn new financial software

• Intermediate knowledge of MS Excel (V-lookup, formulas, pivot tables).

• Global consolidations experience a plus

• Strong interpersonal and communication skills

• Sound judgment and problem-solving skills

• Bachelor’s or master’s degree in Accounting a MUST, good understanding of GAAP

• 3+ years’ experience working as a staff/senior accountant

• General Ledger/Operational Accounting experience a must

• Extensive knowledge of Quickbooks and other reporting software

• Prior involvement with system implementation

• Prior public accounting experience (any size firm) a plus

• Industry experience a plus

Request Your Aerolase Demo Today!

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